Managed by |
NDM - Centre for Human Genetics |
Location |
HWB GENOMIC MEDICINE, Headington |
Facility |
Cellular Imaging Core Facility |
Availability |
Training, access and collaborative projects open to all internal and external academic and industry groups. |
Shareability |
Yes |
More information |
The Elyra PS1 is a widefield fluorescent microscope which combines TIRF and SMLM modalities in to a single system. Single molecule localisation microscopy uses the phenomenon of fluorophore ‘blinking’ to push the resolution limit of light microscopy down to the 30-40nm scale. TIRF imaging allows high resolution imaging of structures close to the coverslip with fantastic signal to noise ratio, and so is ideal for imaging structural proteins and targets which sit on the cell surface. This system features a dual camera setup, allowing rapid simultaneous multichannel acquisition. |