Description: |
We are a uniquely experienced mass spectrometry laboratory providing a comprehensive suite of accessible, affordable and fast analytical, functional and proteomics services to over 300 scientists across every life science department within the University, to external academic institutions across the UK and abroad as well as commercial companies from the smallest biotech start up to major multinationals. Analyses available include (but is not limited to) difficult proteins including membrane proteins, glycoproteins and macromolecular complexes; proteoform primary structure; all types of PTM characterization; chemical modification including ADCs; protein-protein interactions; protein-ligand interactions including drugs, fragments & natural ligands; ligand specificity and affinity; protein conformational fold including size, shape, stable conformers and changes in conformation; functional assays including substrate conversion; protein specific activity and monodispersity; quantitative proteomics; protein crosslinking; immunoprecipitation; small molecules, peptides & nucleic acids; absolute quantitation of drug substances from serum. We have over 28 years of MS experience and access to the latest LC-MSMS equipment and software. Please discuss your experimental requirements and obtain a quotation before submitting samples. |