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Experienced mass spectrometry laboratory offering proteomics services to to all the life science departments within the University, to external academic institutions across the UK and abroad as well as commercial companies from the smallest biotech start up to major multinationals.
Analyses available include the following:
- difficult proteins including membrane proteins, glycoproteins and macromolecular complexes
- ligand specificity and affinity
- protein conformational fold including size, shape, stable conformers and changes in conformation
- functional assays including substrate conversion; protein specific activity and monodispersity
- quantitative proteomics
- protein crosslinking
- immunoprecipitation
- small molecules, peptides & nucleic acids
- absolute quantitation of drug substances from serum.
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