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The Biophysics and Biochemistry group specialises in small molecule drug discovery projects within the Centre for Medicines Discovery. We carry out assay development, high throughput screening campaigns and the subsequent biophysical and biochemical characterisation of lead compounds. The group has been supporting the discovery of probes for 13 years and has worked with the medicinal chemistry groups in the University of Oxford, outside collaborators in academia and industry, and multinational consortia.
Our expertise is available through a small research facility (SRF). We are offering a range of services from supporting you in assay development and miniaturisation to carrying out assay development, screening campaign and lead characterisation for you.
We can support with assay development for challenging targets, covering a wide range of technologies: (see below)
- Assay miniaturisation to 384 well and 1536 well microtiter plate formats
- Access to the screening libraries with >100,000 compounds
- Conducting high throughput screening campaigns on our platforms
- Lead validation and characterisation with biophysical methods
- Time and training on our equipment if you have specific needs you can’t address in your own lab
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