MS IDREC application process

Before you start

In general, the MS IDREC reviews ethics applications for research involving human participants, human tissue (where the tissue is not relevant material under the Human Tissue Act) and/or personal data, from researchers based in (or linked to) a department in the Medical Sciences Division or Mathematical, Physical and Life Science Division. The exception to this is the department of Computer Science, which has its own Departmental Research Ethics Committee (DREC)).

The route you will need to follow in order to obtain ethics review and approval for your research will depend on a number of factors.

  1. Check the Where and how to apply flowchart to determine whether you will need to apply for ethics approval from an NHS research ethics committee instead of from the MS IDREC.
  2. If your research involves only previously collected, anonymous, biological samples, please complete the form specifically for these studies:
  3. If your research involves only analysis of potentially identifiable secondary data, please complete the form specifically for these studies:
  4. If you do not need to apply for NHS ethics approval, and items 2 and/or 3 do not apply, please work through our application decision tool to determine how to apply for ethics review and approval of your research.

You may find it helpful to refer to our frequently asked questions, which cover topics such as:

  • Do I need ethics approval? 
  • Completing the CUREC application
  • Data management

If you have not received any ethics-related training before, you should complete either our online research integrity course or one of the face-to-face ethics courses before you start completing your ethics application. The core module of the University’s research ethics and integrity training is compulsory for all new researchers and students, before commencing any research. Experienced researchers who have not completed any formal training in the past 3 years should complete our online refresher training module on research integrity.

Some departments require ethics applications to be reviewed internally before submission to the MS IDREC – check with your departmental administrator and see below. This is definitely the case if your study involves Magnetoencephalographic (MEG) recordings, Magnetic Resonance Imaging (MRI), Transcranial Magnetic Stimulation (TMS) or Transcranial Electrical Stimulation (TES or TCS), or if you are from the Department of Engineering or the Department of Women's & Reproductive Health.

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All CUREC documents are subject to ongoing review. Please always refer to this page (rather than locally stored versions) for the current versions of application forms.


When writing the application, use language accessible to a non-expert audience, explaining your project methods clearly and simply. Include a clear description of potential ethical issues and how you propose to address them. Remember that the ethics committee partially relies on your expertise as a researcher in your field, in order to be clear about the ethics of a project.

Please follow the instructions in Before you start above to determine which form to complete.

A CUREC 1 form is completed for lower-risk research, unless this research involves using only previously collected biological samples or analysis of secondary data only.

A CUREC 2 form is usually required where:

  • you know your project has complex or higher risk ethical issues or cites more than one approved procedure (and those procedures do not state they can be used together)
  • completion of the MS IDREC online application decision tool directs you to complete a CUREC 2 application

The CUREC 3 ethical review process should be followed where any licensed drug or other (non-drug) substance is to be administered to healthy volunteers for the purposes of research. This may include food supplements or herbal remedies. It may also be required for research involving certain medical devices. Please speak to the MS IDREC secretariat before completing any application involving medical devices. 

If your research will involve using only previously collected, anonymous, biological samples, please complete the form specifically for these studies:


If your research involves only analysis of potentially identifiable secondary data, please complete the form specifically for these studies:




It is likely your application will need supporting documents, either for external (participant) or internal (researcher) use.

Documents for external use may include (but are not limited to):

  • recruitment adverts/invitation letters/emails
  • information sheet(s)
  • written consent and/or assent forms
  • surveys or questionnaires (paper or online)
  • debrief information

Please see our page on informed consent for more details and templates. If you follow a CUREC approved procedure, please use the procedure-specific participant information sheets and consent forms as well as any other supporting documents associated with that procedure.

For CUREC 3 applications, you should use the template information sheet and consent form specifically for these higher risk studies.

Documents for internal use include sample research instruments (researcher-completion surveys or questionnaires, semi-structured interview guides) detailed study procedures and risk-assessments.

Please note that submission of a protocol is not a requirement for research reviewed by the MS IDREC unless your study requires University Sponsorship and Health Research Authority (HRA) review in addition to our ethics approval, or is a CUREC 3 application.  All information should instead be on the application form. If you do need to provide a protocol for a CUREC 1 or CUREC 2 application, please use this template:


Applications are reviewed on a continuous basis, in the order of receipt of a valid (complete) application.  There are no deadlines for submission.

Your full application (including all supporting documents) should be sent by email to the MS IDREC Secretariat (

Before an application can be reviewed, a signature or email endorsement is needed from the PI, the student (if student research) and the head of department or delegated nominee. 

Applications are not valid until all signatures and supporting documents have been provided to the MS IDREC.

The IDREC want to see final versions of all research documents in order to check compliance with the relevant University policy.


The MS IDREC Secretariat will acknowledge receipt of your application (please allow five working days for this) and initiate the review process. Once reviewed, you will receive feedback via email, which may request changes or further information. Once all documents have been updated and questions answered to the satisfaction of the MS IDREC, you will receive an approval letter. You may not start your study until you receive this letter.

The timeframe for review depends on the study risk, quality of the application and supporting documents, and committee workload. Note that the review clock starts when we have received all required documents for review. It stops while we are waiting for revisions from you.

  • CUREC 1 - Up to 30 days
  • CUREC 2 - Up to 60 days*
  • CUREC 3 - Usually within 60 days*

* CUREC 2 and CUREC 3 applications are considered by the full committee via correspondence. Should there be any ethical concerns raised, it may be necessary to refer CUREC 3 applications for review at the next MS IDREC termly meeting.



In extremely rare cases we may not be able to provide ethics approval. An appeals procedure is available for appealing a decision to withhold, suspend or withdraw approval of research:

Some departments have internal processes whereby all ethics applications must be reviewed within the department prior to submission to the MS IDREC. Please check with your departmental administrator for further details. If your application cites the CUREC approved procedures for Magnetoencephalographic (MEG) recordings, Magnetic Resonance Imaging (MRI), Transcranial Magnetic Stimulation (TMS) or Transcranial Electrical Stimulation (TES or TCS), or if you are from the departments of Engineering Science or Women's & Reproductive Health, your application must be reviewed as follows:

Procedures requiring departmental review
Procedure Contact Additional information
MRI Nancy Rawlings FMRIB/OHBA MRI ethics procedure
MRI with TCS or TMS Nancy Rawlings Reviews will be conducted by both Nancy and one of Charlotte Stagg, Jacinta O'Shea and Melanie Fleming, but should be submitted to Nancy.
Please include the WIN NIBS Internal Review Form when submitting a review.
TCS or TMS only Nancy Rawlings Reviews will be conducted by Charlotte Stagg, Jacinta O'Shea or Melanie Fleming, but should be submitted to Nancy.
Please include the WIN NIBS Internal Review Form when submitting a review.
MEG  Sven Braeutigam   
Engineering Science Tamara Lawson The applications will be checked in the first instance by the Research Office and then signature by the HoD will be arranged
Women's & Reproductive Health

Sharon Westcar

Lucy Kingham




As your project progresses, there may be reasons to make changes (for example to principal investigator (PI), participant-facing documents, or procedures), known as amendments. These must be notified to the MS IDREC for consideration and approval. Please complete the amendment form and email it to the

You will also need to send any new or revised documentation, which must have changes highlighted, preferably using MS Office Word tracking so that deleted and revised text can both be seen. If your original application required departmental review, revised documentation must first be sent to the department for continued approval. Approval of continued University sponsorship, where sought as part of the original application, will also be required before MS IDREC review.

You must not carry out your study with the changes applied until you receive confirmation of continued ethics approval from the MS IDREC Secretariat. If the changes are significant and the project substantively altered, you may need to complete a new application form. See section E on our FAQs page for further details and guidelines on amendment classification.

See the 'After approval' section of our FAQs for details.



The committee may ask to review your project, or for you to complete an annual progress report as part of routine monitoring exercises. Please always make sure you have the most up to date study procedures, supporting information and approval letters to hand, for ease of review.

Please note that researchers conducting studies approved via the CUREC 2 or CUREC 3 application route that have a duration of more than one year, are required to submit annual progress reports.


In the event that a complaint is made about research approved by this research ethics committee, it should be referred to 

Where it becomes apparent that there has been a serious breach of the terms of the ethical approval, this will be communicated to the research ethics committee.

Any complaints about the committee itself should be made to CUREC:

If you have any questions about the application process or about addressing the ethical issues in your research contact us at