Oxford Tropical Research Ethics Committee (OxTREC)

The Oxford Tropical Research Ethics Committee (OxTREC) is one of CUREC’s three subcommittees. It is responsible for reviewing the ethics of University medical research involving human participants and personal data which takes place outside the EU, or where the research is funded by the US National Institutes of Health or another US federal funding agency. OxTREC review does not replace the need for ethical review within the country where the research will take place.

 

CURECCTRGMS IDRECSSH IDRECDRECs

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The committee is constituted in accordance with the University regulations on CUREC subcommittees (Part 13 of Council Regulations 15 of 2002). These regulations, in conjunction with the standing orders of OxTREC, detail the remit of the committee, its responsibilities, requirements for quorum, and requirements (for the committee and researchers) for record keeping and audit.

The committee includes members from a range of academic and non-academic disciplines. Some members are internal to the University and have academic positions. Of the academic members, some are 'research active' but others are not currently involved in research with human participants or personal data.

The committee also has external members who bring valuable expertise and perspectives from non-academic and non-educational sectors. In this way it is hoped the members together reflect the interests of researchers, participants and third parties. Appointed members serve for four years and are re-eligible. For full details of committee membership requirements, see Part 13.8 of the Council Regulations.

Please note: any queries about the committee should be sent directly to oxtrec@admin.ox.ac.uk and not to individual members.

 

  Name Department Conditions of appointment Until start of
[1] Professor Kevin Marsh (Chair) Nuffield Department of Medicine Two persons appointed as chair and vice-chair of the subcommittee by the Research Committee of Council, ideally one of whom shall not currently be involved in research involving human participants or personal data. The person appointed as vice-chair may be external. MT 2020
[2] Professor Persephone Borrow (Vice-Chair) Nuffield Department of Medicine As above
 
MT 2022
[3] Ms Catherine Barnes External One person, who may be external, appointed by CUREC on the recommendation of the chair of the relevant subcommittee whose primary personal or professional interest is not in research involving human participants or personal data MT 2019
[4] Mr Andrew Taylor External One person, who may be external, appointed by CUREC on the recommendation of the chair of the relevant subcommittee whose primary personal or professional interest is not in any particular research area MT 2018
[5] Dr Ly-Mee Yu Nuffield Department of Primary Care Health Sciences No fewer than three, and no more than eight, persons, one of whom may be external, appointed by CUREC on the recommendation of the chair of the subcommittee, who have methodological and ethical expertise relevant to the proposals which each subcommittee will be expected to scrutinise MT 2018
[6] Dr Matthew Scarborough Oxford University Hospitals NHS Trust As above MT 2021
[7] Dr Angeliki Kerasidou Ethox Centre; Nuffield Department of Population Health As above MT 2021
[8] Dr Jenny MacLennan Department of Zoology As above MT 2021
[9] Dr Andrew Brent Oxford University Hospitals NHS Trust As above MT 2021
[10] Mr Musaiwale Kamfose Oxford University Hospitals NHS Trust As above TT 2019
[11] Professor Vicki Marsh Nuffield Department of Medicine As above HT 2021
Co-opted (The subcommittee may co-opt up to four additional members, who may be internal or external, and who shall hold office for such period as the subcommittee may determine)
[12] Dr Laura Watson External Co-opted TT 2021
[13] Dr Fiona Groenhout Social Sciences Division Co-opted TT 2020
[14] Dr Ariella Binik Ethox Centre, Nuffield Department of Population Health Co-opted MT 2018

Secretary: Dr Rebecca Bryant

 

OxTREC delegates review of minimal risk applications to the OxTREC secretariat where appropriate. Minimal risk applications are  reviewed on a rolling basis. All other applications are reviewed by the full committee, which meets six times a year.

Whether a study qualifies as minimal risk or not is a decision taken by OxTREC and not the applicant. See the OxTREC application process page for further information about the application process.
 

This table lists studies approved by OxTREC since January 2018.

OxTREC ref. PI name Study title Research type Countries involved Approval date
1-18 Philippa Matthews OXSAHep (Oxford-South Africa Hepatitis) Study: Defining host and viral factors that are associated with hepatitis B virus (HBV) control and clearance in Caucasian and African adults Clinical research UK, South Africa 3/1/18
557-17 Direk Limmathurotsakul Health burdens of antibiotic resistant infection in Southeast and South Asia - a multinational retrospective study Minimal risk Cambodia, Indonesia, Thailand, Lao PDR, Myanmar, Vietnam, Nepal 4/1/18

 

This table lists studies approved by OxTREC since January 2017. 

OxTREC ref.

PI name

Study title

Research type

Countries involved

Approval date

56-16

Stephen Baker

An open single-arm interventional study to identify the influence of human genetic variation on early transcriptional responses and protective immunity following immunization with rotavirus vaccine in Vietnamese infants

Clinical research

Vietnam

12/1/17

51-16

Fazle Rabbi Chowdhury

 

Is melioidosis a significant cause of febrile admissions for people with and without diabetes in Bangladesh?

Clinical research

Bangladesh

12/1/17

501-17

Mark McCarthy

 

Analysis of whole exome sequence data from the T2D-GENES project

Minimal risk

UK

12/1/17

502-17

Richard Gibbons and Sachith Mettananda

Co-inheritance of α-thalassaemia among patients with β-thalassaemia

Minimal risk

Sri Lanka

12/1/17

57-16

Kevin Baird

 

Feasibility of the Nanobubble Technology for Detection of Malaria

Other research

Indonesia

13/1/17

504-17

Claudia Turner

Utilisation of a clinical microbiology service in a low income country paediatric hospital: the impact on antibiotic prescribing practices and barriers and facilitators to use

Minimal risk

Cambodia

18/1/17

49-16

Rose McGready

 

Prevention of mother-to-child transmission of hepatitis B virus (PMTCT-HBV): Hepatitis B Policy and Practice in Northern Thailand and Tenofovir in early pregnancy: a one arm, open label intervention study to estimate the optimal timing of Tenofovir (TDF)

Clinical research

Thailand

19/1/17

5128-16

 

Sassy Molyneux

A preliminary study towards understanding the potential role of Clinical Learning Systems in Kenya: Experiences and attitudes of key health and research stakeholders on the Kenyan Coast

Minimal risk

Kenya

25/1/17

503-17

Daniel Parker

Movement and migration patterns among a cohort of villagers from the Thailand-Myanmar border

 

Minimal risk

Thailand, Myanmar

25/1/17

52-16

Guy Thwaites

 

A randomized double blind placebo controlled trial of adjunctive dexamethasone for the treatment of HIV-uninfected adults with tuberculous meningitis stratified by Leukotriene A4 hydrolase genotype

Clinical research

Vietnam

27/1/17

1-17

Jay Berkley

 

First Line Antimicrobials in Complicated Severe Acute Malnutrition

Clinical research

Kenya, Uganda

8/2/17

505-17

Stephen Baker

The diversity of the gut microbiota and its role in antimicrobial resistance gene circulation in healthy Vietnamese people

Minimal risk

Vietnam

10/2/17

54-16

Lorenz von Seidlein

 

Safety and Immunogenicity evaluation of the malaria vaccine RTS,S/AS01, in healthy Thai adults

Clinical research

Thailand

16/2/17

2-17

 

Bronwyn Myers

Strengthening South Africa’s health system through integrating treatment for mental illness into chronic disease care: A cluster randomized controlled trial

Clinical research

South Africa

21/2/17

47-16

Eduard Sanders

 

Targeted Research Advancing Sexual Health for Men who have sex with Men (TRANSFORM)

Clinical research

South Africa, Kenya

22/2/17

509-17

Rose McGready

Nutrition in transition: local perceptions of under- and over-nutrition in pregnancy in marginalized Burman and Karen communities along the Thailand-Myanmar border

 

Minimal risk

Thailand, Myanmar

23/2/17

508-17

Paul Turner

Trends in antimicrobial resistance in invasive bacterial infections in hospitalised Cambodian children, 2007-2016

Minimal risk

Cambodia

27/2/17

53-16

 

Nicholas Day

Assessing the tolerability and safety of single low dose primaquine in African children with acute uncomplicated falciparum malaria and glucose 6 phosphate dehydrogenase deficiency (BAKMAL1606)

Clinical research

Uganda, Democratic Republic of Congo

1/3/17

507-17

Maria Chiara Rizzi

Testing the role of RDTs as a Point of Care tool in the early diagnosis of melioidosis: a pilot comparison with culture in Laos, an endemic region

 

Minimal risk

Laos

2/3/17

511-17

Christoffer Nellåker

Aiding computational phenotyping of facial features by inheritance modelling

Minimal risk

Worldwide (internet-based)

7/3/17

4-17

 

Daniel Paris

The Scrub Typhus Antibiotic Resistance Trial (START). Comparing Doxycycline and Azithromycin Treatment Modalities in Areas of Reported Antimicrobial Resistance for Scrub Typhus

Clinical research

Thailand

8/3/17

5-17 Jeremy Day Open label phase III, single center trial to assess the efficacy, safety, tolerability, and pharmacokinetics of sofosbuvir plus ravidasvir in HCV (+/- HIV) chronically
infected adults with no or compensated cirrhosis in Vietnam
Clinical trial Vietnam    17/3/17
506-17 Direk Limmathurotsakul Antibiotic Feed in Animal Farm in Thailand – Pilot Questionnaire Study Minimal risk Thailand 29/3/17
516-17 Jordi Landier ELISA validation of hypersensitive rapid diagnostic test results for detection of P. falciparum using field samples from prevalence surveys Minimal risk Thailand 4/4/17
3-17 Ni Ni Tun A clinical and pharmacokinetic study of the effectiveness of Hepatitis C treatment to HIV co-infected and non HIV co-infected patients at the level of non-hospital based management in Myanmar Clinical research Myanmar 5/4/17
519-17 Peter Hammond Image Analysis of Neurofacial Effects of Prenatal Alcohol Exposure Minimal risk UK (US federal funding) 5/4/17
515-17 Clifford George Banda Tools for quality data: Understanding the available resources and tools for setting up and conducting malaria clinical trials in low and middle income countries within malaria endemic settings Minimal risk DRC, Ethiopia, Kenya, Malawi, Thailand, Burkina Faso, Ghana, Senegal 6/4/17
512-17 Florian Marks Real-time Tracking of Neglected Bacterial Diseases and Resistance Patterns in Asia Minimal risk Cambodia, Vietnam 11/4/17
513-17 Brian Parkinson The impact of emotion regulation on cooperation and trust Minimal risk UK (US federal funding) 12/4/17
518-17 Anisha Gururaj Evaluating the role of a semi-automated ultrasound device in rural Indian antenatal care Minimal risk India 26/4/17
13-17 Jeremy Day Continuous infusion vs. intermittent bolus dosing of ceftriaxone for the treatment of bacterial meningitis: a randomized pharmacokinetic and pharmacodynamic comparison Clinical trial Vietnam 27/4/17
12-17 Philip Bejon A Phase IV randomized, double blinded non-inferiority trial on the immunogenicity and safety of fractional doses of yellow fever vaccines Clinical trial Kenya, Uganda 27/4/17
514-17 Derrick Bennett Objective measurement of physical activity in urban and rural Chinese: A feasibility study Minimal risk China    4/5/17
521-17 Halina Suwakowska Ethical and socio-cultural aspects of autopsy in low and middle-income countries Minimal risk Vietnam, Nepal 4/5/17
520-17 Thomas Darton Investigating colonisation by fluoroquinolone-resistant Enterobacteriaceae in the gastrointestinal microbiota of children living in urban and rural areas of Vietnam Minimal risk Vietnam 4/5/17
48-16 Nick White Assessing the tolerability of a potentially safer radical curative regimen of primaquine in healthy volunteers with glucose 6 phosphate dehydrogenase deficiency in Thailand Clinical trial Thailand 11/5/17
5117-16 Issac Lim Preparing the healthcare workforce for future populations: a Cultural Historical Activity Theory (CHAT) perspective Minimal risk Singapore 11/5/17
522-17 Frances Gardner Feasibility study of an evidence-informed parenting intervention to prevent violence against young children by parents and caregivers in Thailand: Phase One Minimal risk Thailand 23/5/17
10-17 Serena Vickers A pilot study of the clinical and biochemical phenotype of diabetes in Vientiane, Lao PDR Clinical research Lao PDR 31/5/17
526-17 Mehul Dhorda Prevalence survey of plasmodium falciparum antimalarial drug resistance markers at sites in India Minimal risk India 1/6/17
14-17 Amina Abubakar Adolescent Executive Functioning and its Association with Scholastic Outcomes, Mental Health Outcomes, Health Risk Behavior and Medical Adherence in the Context of HIV Other research Kenya 6/6/17
16-17 Nguyen Thi Hoang Mai A Prospective Observational Study Aiming at Improving Diagnosis in Patients with Central Nervous System Infections in Vietnam Clinical research Vietnam 8/6/17
525-17 Olga Tosas Auguet Preliminary Exploration of Infection Prevention and Control and Antibiotic Stewardship (IPC-ABS) to Avert Antibiotic Resistance in Kenyan Hospitals Minimal risk Kenya 14/6/17
527-17 Mallika Imwong Prevalence survey of plasmodium falciparum antimalarial drug resistance markers in Greater Mekong Subregion Minimal risk Thailand, Myanmar, Laos, Vietnam, Cambodia 14/6/17
528-17 Marco Haenssgen Antibiotics and Activity Spaces: An Exploratory Study of Behaviour, Marginalisation, and Knowledge Diffusion Minimal risk Thailand, Lao PDR 14/6/17
46-16 Eduard Sanders Impact of a novel HIV-1 RNA testing intervention to detect acute and prevalent HIV infection and reduce HIV transmission – Tambua Mapema Plus Clinical trial Kenya 21/6/17
5124-16 Nazla Lufthee Antimicrobial susceptibility of bacterial isolates causing Urinary Tract Infections Minimal risk Maldives 21/6/17
524-17 Rose McGready Establishing best methods for patient education and public health messaging in populations with low literacy on the Thailand Myanmar border Minimal risk Thailand, Myanmar 21/6/17
20-17 Nicholas Yeung Decision Confidence in Human-Machine Teaming Other research United Kingdom 22/6/17
18-17 Frank Smithuis A multicentre observational study to describe the prevalence of scrub typhus, defined as a positive rapid diagnostic test, among selected patients presenting with fever to clinics in Myanmar Clinical research Myanmar 5/7/17
517-17 Kyaw Myo Tun Ethical issues in recruitment of teenagers and young people in clinical research in Myanmar Minimal risk

Myanmar

5/7/17
532-17 Maia Rabaa Phylogenetics and Epidemiology of Zika in Southern Vietnam Minimal risk Vietnam 5/7/17
11-17 Sasithon Pukrittayakamee Efficacy and safety of KAF156 in combination with LUM -SDF in adults and children with uncomplicated Plasmodium falciparum malaria Clinical trial Thailand 12/7/17
529-17 Phaikyeong Cheah In Their Own Voices: Vulnerabilities & Abilities of Women, Children, & Families in Health Research on the Thai-Myanmar border Minimal risk Thailand, Myanmar 14/7/17
19-17 Direk Limmathurotsakul Utility of Sepsis-3 definition, causes and factors associated with outcomes in community-acquired sepsis in Ubon Ratchathani, Northeast Thailand Clinical research Thailand 17/7/17
17-17 Lauren Carrington Active surveillance of arbovirus infections in Aedes mosquitoes and humans in HCMC Clinical research Vietnam 17/7/17
533-17 Abhilasha Karkey Knowledge assessment and perspectives on antimicrobial resistance among pharmacists in Lalitpur metropolitan city Minimal risk Nepal 17/7/17
530-17 Tinashe Brian Chandauka Human Factors in Southern African Surgery: A study of the knowledge, attitude and practices of Southern African surgical practioners with regard to perioperative patient safety and a pilot of a human factors training programme Minimal risk South Africa, Zambia 20/7/17
26-17 James Berkley Intravenous and Oral Fosfomycin in Hospitalised Neonates with Clinical Sepsis: an open-label safety and pharmacokinetic study Clinical trial Kenya 2/8/17
15-17 Andrew Pollard Assessing the impact of a Vi-Polysaccharide Conjugate Vaccine in preventing typhoid infections among Nepalese children – a Phase III trial Clinical trial Nepal, Vietnam 10/8/17
535-17 Sophie Yacoub Markers of macrophage activation syndrome in the pathogenesis of severe dengue Minimal risk Vietnam 11/8/17
534-17 Phaikyeong Cheah In Their Own Voices: Vulnerabilities & Abilities of Women, Children, & Families in Health Research in Chiang Rai Province Minimal risk Thailand 17/8/17
5123-16 Paul Turner Seroprevalence of Dengue Virus and Rickettsial Infections in Cambodian Children Minimal risk Cambodia 31/8/17
531-17 David Clark Internet-based cognitive-behavioural therapy for social anxiety disorder in the Chinese population Minimal risk China 31/8/17
538-17 Marco Haenssgen The evolution of antibiotic demand and supply among private and informal healthcare providers in Chiang Rai Minimal risk Thailand 6/9/17
540-17 Mary Chambers Issues surrounding the Expanded Program on Immunization (EPI) and
Maternal and Neonatal Tetanus (MNT) program uptake in ethnic minorities in
Dak Lak Province Viet Nam
Minimal risk Vietnam 19/9/17
541-17 Cindy Chu Retrospective Study to assess the rate of Plasmodium vivax infections
presenting with severe symptoms from 2001 to 2016 in north-western Thailand
Minimal risk Thailand 19/9/17
536-17 Mira Schneiders Care needs and responsibilities among older people in Cambodia: lived experiences and ethical issues Minimal risk Cambodia 19/9/17
542-17 Ngo Thi Hoa Comparative genomic analysis of Escherichia coli isolated from animals, healthy individuals and patients Minimal risk Vietnam 21/9/17
539-17 Mary Chambers Issues surrounding tetanus toxoid vaccination uptake and delivery in 3 communes in Binh Phuoc Province Minimal risk Vietnam 4/10/17
545-17 Mehul Dhorda Performance and cost-effectiveness of an Automated Malaria Microscopy device (Autoscope version 3) in research settings Minimal risk Bangladesh, Thailand, Cambodia 6/10/17
25-17 Joel Tarning Randomised Open-Label, Single-Dose, Cross-Over Study to Evaluate the Bioequivalence of a New Parenteral Formulation of Artesunate with the Currently Used Formulation in Healthy Adult Thai Subjects Clinical trial Thailand 17/10/17
546-17 Gracia Fellmeth Exploring the aspirations of new Karen mothers on the Thai-Myanmar border Minimal risk Thailand, Myanmar 19/10/17
544-17 Behzad Nadjm Patient safety, hospital acquired infection and antibiotic resistance in the hospital – a lay perspective from Vietnam Minimal risk Vietnam 26/10/17
22-17 François Nosten Developing a methodology to assess 8-aminoquinoline associated haemolytic risk in females heterozygous for G6PD in endemic populations Clinical research Thailand 1/11/17
551-17 Mamy Jean de Dieu Randria Clinical characterization and microbiological diagnosis of patients presenting to plague treatment centres with suspected pneumonic plague in the 2017 Madagascar outbreak Clinical research Madagascar 3/11/17
547-17 Claudia Turner Design, implementation and assessment of a comprehensive community neonatal health package utilising medical and social interventions Minimal risk Cambodia 6/11/17
543-17 Trudie Lang Knowledge Gap Analysis of Clinical and Laboratory Research Capacity in Central and South America Minimal risk Central and South America 8/11/17
549-17 Nina Hallowell Facing ethics: Identifying ethical issues in computational phenotyping research Minimal risk UK, US, EU, Australia 8/11/17
29-17 Simon Draper A Phase Ib age de-escalation dose-escalation randomised, double-blind, controlled study of the safety and immunogenicity of heterologous prime-boost with the candidate malaria vaccines ChAd63 RH5 and MVA RH5 administered intramuscularly according to a 0, 2-month vaccination schedule in healthy adults, young children and infants in Tanzania Clinical trial
(Pan African Clinical Trial Registry: PACTR201710002722229)
Tanzania 15/11/17
34-17 Shrijana Shrestha Persistence of Immunity Following an Open Label, Randomised Controlled Non-inferiority Trial, Comparing Two-Dose Priming with the 10-Valent Pneumococcal Conjugate Vaccine at 6 and 10 weeks to 6 and 14 Weeks, in Nepali Children Clinical research Nepal 15/11/17
548-17 Deena Al Asfoor Qualitative Validation of Access-29 and HRQOL Diabetes-39 in Omani Diabetic patients Minimal risk Oman 16/11/17
550-17 Claudia Turner Ethical issues around healthcare provision in a low-resource setting from the perspective of hospital staff and end users Minimal risk Cambodia 22/11/17
32-17 Arjen Dondorp A multi-centre, open-label randomised trial to assess the efficacy, safety and tolerability of the Triple ACT artemether lumefantrine+amodiaquine (AL+AQ) compared to the ACT artemether-lumefantrine (AL) in uncomplicated falciparum malaria in Cambodia and Vietnam Clinical trial (clinicaltrials.gov:  NCT03355664) Cambodia and Vietnam 30/11/17
554-17 Paul Turner Characterisation of Cambodian Burkolderia pseudomallei glycan/lectin binding profiles Minimal risk Cambodia 30/11/17
24-17 Guy Thwaites A prospective observational study of the host and bacterial determinants of outcome from multi-drug resistant pulmonary tuberculosis Clinical research Vietnam 6/12/17
33-17 Guy Thwaites A prospective observational study of the host determinants of outcome of drug susceptible pulmonary tuberculosis Clinical research Vietnam 6/12/17
31-17 Alan Stein Cluster Randomised Trial to evaluate an intervention for depressed HIV-positive women in the perinatal period, to enhance child development and reduce maternal depression Clinical trial (ISRCTN Registry: ISRCTN11284870 & South African National Clinical Trial
Register: NHREC # 4889)
South Africa 6/12/17
556-17 Valentina Iotchkova Analysis and statistical method development for uncovering and understanding genetic variation underlying complex cardiovascular and haematological traits Minimal risk US 7/12/17
537-17 Maureen Kelley Resilience, empowerment, and advocacy in women’s and children’s health research (REACH) in KwaZulu-Natal Minimal risk South Africa 8/12/17
553-17 Natalie van Zuydam Large-scale targeted sequencing of genomic regions associated with coronary heart disease in subjects with peripheral arterial disease Minimal risk US 13/12/17
552-17 Sonia Lewycka Household survey of antibiotic use and carriage of resistant bacterial isolates in preparation for a trial Minimal risk Thailand 19/12/17
36-17 Paul Turner A pilot observational study to determine nasopharyngeal microbiota dynamics in Cambodian children Clinical research Cambodia 20/12/17

 

It was agreed by CUREC in early 2016 that, in the interest of transparency, OxTREC should make publicly available a list of studies that it has approved. The list below sets out those studies that have been approved by OxTREC since January 2016.

OxTREC ref.

PI name Study title  Research type  Countries involved  Approval date 
49-15 Yoel Lubell  The impact of C-reactive protein testing on antibiotic prescription in febrile patients attending primary care in low-resource settings  Clinical research  Thailand, Myanmar, Democratic Republic of Congo (DRC)  11/1/16 
46-15 Daniel Paris  Eschar investigations to improve diagnostics, understand early immune responses and characterize strains for vaccines in scrub typhus (EXIST)  Clinical research  Thailand 12/1/16 
579-15   Paul Turner  An exploration of vertical transmission of multi-drug resistant Gram negative organisms in Cambodian mother-infant pairs (Mother-Infant Colonisation Study: MIC)  Minimal risk Cambodia  19/1/16 
581-16  Claudia Turner  Exploring and Understanding the Community Attitudes toward Research Ethics in Cambodia  Minimal risk  Cambodia  27/1/16 
577-15  Patricia Kingori  What are the emotional, ethical and logistical realities of employment in an Ebola Treatment Unit? The views of local frontline staff  Minimal risk  Sierra Leone  27/1/16 
47-15  James Berkeley  First Line Antimicrobials in Complicated Severe Acute Malnutrition – preliminary pharmacokinetics and faecal carriage components  Clinical research  Kenya  12/2/16
4-16  Denis Noble  Effects of Glycyrrhetic Acid & other Chemical Components of TJ-68 on Physiological Mechanisms in Healthy Humans Clinical research   USA   12/2/16 
583-16  Rose McGready  Causes and impact of anemia on pregnancy outcome on the Thai-Myanmar Border: cost-effective diagnostic and treatment algorithms  Minimal risk  Thailand, Myanmar  12/2/16 
585-16  Sophie Janet  Outcomes of neonatal resuscitation in a resource limited setting on the Thailand-Myanmar border  Minimal risk  Thailand, Myanmar  16/2/16 
584-16  Chris Paton  Survey of Electronic Health Records (EHR) systems used in public hospitals in Kenya  Minimal risk  Kenya  18/2/16 
2-16  Philip Bejon  Controlled Human Malaria Infection (CHMI) to assess human immunity to P. falciparum using sporozoites administered by direct venous inoculation  Clinical trial  Kenya  24/2/16 
5-16  Borimas Hanboonkunupakarn  Open-Label Study to Evaluate Potential Pharmacokinetic Interactions of Orally Administered Artemether-lumefantrine, Amodiaquine and Primaquine in Healthy Adult Subjects  Clinical trial  Thailand  25/2/16 
3-16 François Nosten Impact of malaria infection in pregnancy on fetal and newborn growth – child follow-up until 2 years of age, in relation to the fetal growth Clinical research Thailand 8/3/16
582-16 Caroline Jones The Acceptability & Potential for Scale-up of House Modifications used in the RooPfs Study in The Gambia  Minimal risk The Gambia 8/3/16
586-16 Carl Britto Estimating the in-patient burden and antibiotic resistance pattern of enteric fever in a tertiary care hospital in South India Minimal risk India 10/3/16
13-16 Carine Asnong Perceptions and experiences of teenage pregnancies in refugee and migrant women and adolescents on the Thai-Myanmar border  Minimal risk Thailand 7/4/16
580-16 Michael Parker Developing a robust and supportive ethical and governance framework for genomic research in Africa – an exploratory study in Ghana, Uganda and Zambia Minimal risk  Ghana, Uganda, Zambia 8/4/16
15-16 Buddha Basnyat Parallel group, double blinded, 1:1, randomized controlled phase III trial of co-trimoxazole versus azithromycin for the treatment of undifferentiated fever in Nepal Clinical trial Nepal 21/4/16
17-16 Louise Thwaites Intrathecal Immunoglobulin for treatment of adult patients with tetanus: a randomized controlled 2x2 factorial trial Clinical trial  Vietnam 27/4/16
18-16 Son Do Hung Randomised controlled trial to estimate the fraction of malaria infections attributable to forest work  Clinical trial Vietnam 27/4/16
16-16 Richard Idro Antibodies to Neuron Surface Proteins, infection by Onchocerca volvulus and the Pathogenesis of Nodding Syndrome; a Case Control Study Clinical research Uganda 28/4/16
12-16 Richard Idro Doxycycline for the treatment of nodding syndrome: A phase II, randomized placebo controlled trial Clinical trial Uganda 28/4/16
8-16 Cristian Capelli The Genomic Landscape of African Populations Other research South Africa, Lesotho, Namibia, Malawi, Mozambique, Tanzania 6/5/16
592-16 Bridget Wills The prevalence of Zika and Chikungunya viruses in Asian patients with undifferentiated fever Minimal Risk Countries across Latin America and Asia 13/5/16
593-16 Elizabeth Pisani What makes data sharing work? WWARN case study Minimal Risk N/A 16/5/16
19-16 Mayfong Mayxay A randomised, double-blinded controlled treatment trial of subclinical vivax infections with primaquine in Nong province, Laos Clinical Trial Laos 18/5/16
594-16 Nzelle Delphine Kayem The ZIKV Minimal Dataset Determination Study Minimal Risk Brazil 6/6/16
588-16 Stephen Baker The perception and usage of probiotics and antibiotics by parents in Ho Chi Minh City, Vietnam Minimal Risk Vietnam 13/6/16
25-16 Jeremy Day A randomized phase 2 trial of Tamoxifen boosted antifungal therapy for cryptococcal meningitis Clinical Trial Vietnam 16/6/16
590-16 Francois Nosten Determination of the sensitivity and specificity of the BD MicroImager (BDMI) for detection of acid fast bacilli (AFB) in a clinical setting Minimal Risk Thailand  21/6/16 
596-16 Louise Thwaites Muscle Mass and Functional Outcome in Tetanus Survivors at the Hospital for Tropical Diseases Minimal Risk Vietnam 22/6/16
591-16 Olivo Miotto Integrating genetic epidemiology as an intensified surveillance tool into the National Centre for Parasitology, Entomology and Malaria Control of Cambodia Minimal Risk Cambodia 23/6/16
31-16 Heiman Wertheim Community-level antibiotic access and use in low- and middle-income countries; finding targets for social interventions to improve rational antimicrobial use Clinical Research Vietnam, Thailand, Bangladesh, Mozambique, Ghana, South Africa 27/6/16
595-16 Ruchi Baxi Sharing infectious disease related data and biological samples from low resource settings: perspectives on ethics and governance Minimal Risk Kenya, Sierra Leone, Liberia 28/6/16
597-16 Manar Marzouk  Management of Cancer Care for refugee populations: the case of Syrian Refugees in Jordan  Minimal risk Syria, Jordan  30/6/16
598-16 Abigail Enoch  Pulse oximeter use in Kenyan hospitals: a qualitative study of health workers’ perspectives of the barriers to pulse oximeter use  Minimal risk  Kenya  5/7/16 
5101-16  Lauren Carrington  Knowledge of dengue and understanding of associated research amongst the community  Minimal risk  Vietnam  15/7/16 
30-16   Annette Fox  How do cross-reactive memory B cells affect influenza vaccine titers  Clinical research  Vietnam, Australia  19/7/16 
48-15  Ivo Elliott  The clinical epidemiology of scrub typhus in humans, chiggers and rodents  Clinical research  Lao PDR  27/7/16 
5102-16  Martha Mwangome  Improving Breastfeeding support to treat acute malnutrition amongst infants under 6 months admitted to hospital because of an illness – A pilot study  Minimal risk  Kenya  28/7/16 
5106-16  Olivo Miotto  Genetic epidemiology of P. falciparum malaria and associated antimalarial drug resistance  Minimal risk  Vietnam, Cambodia, Lao PDR, Thailand, Myanmar  3/8/16 
34-16  James Berkley  The Childhood Acute Illness & Nutrition Network (CHAIN) Building the evidence base for care of acutely ill, undernourished children in limited resource settings – cohort study  Clinical research  Bangladesh, Kenya, Malawi, Pakistan, Uganda  4/8/16 
35-16  Stephen Baker  The clinical features, antimicrobial susceptibility patterns and genomics of bacteria causing neonatal sepsis in a children’s hospital in Vietnam  Clinical research  Vietnam  4/8/16 
599-16  Laura Diment  Temperature and prosthetic discomfort during exercise  Minimal risk  India  4/8/16 
5103-16  Mehul Dhorda  Field Evaluation of a Device for Automated Malaria Microscopy (Autoscope)  Minimal risk  Thailand, Indonesia  10/8/16 
587-16  Tao Dong  International cooperation between China and UK on Immunological and genetic association of virus/pathogen associated cancer development  Minimal risk  China  15/8/16 
36-16  Guy Thwaites  A randomized double blind placebo controlled trial of adjunctive dexamethasone for the treatment of HIV-infected adults with tuberculous meningitis  Clinical trial  Vietnam, Indonesia  16/8/16 
5104-16  Direk Limmathurotsakul  The risk factors and outcomes of community-acquired Acinetobacter bacteraemia in Thailand (MICRO1502_CAB)  Minimal risk  Thailand  16/8/16 
5109-16  Zhengming Chen  Estimating the exposure to ambient and household air pollution among the rural population of China Kadoorie Biobank cohort: a feasibility study  Minimal risk  China  17/8/16 
5111-16  Jeremy Day  Study Laboratory Protocol: A novel approach to improving diagnosis of CNS infections in Vietnam using vibrational spectroscopy  Minimal risk  Vietnam, Australia  17/8/16 
27-16  Tran Tinh Hien  An Open Label, Non-comparative, Multicenter Study to Assess the Pharmacokinetics, Safety and Efficacy of Tafenoquine (SB-252263, WR238605) in the Treatment of Pediatric Subjects with Plasmodium vivax Malaria  Clinical trial  Vietnam  18/8/16 
9-16  Inge Sutanto  A double-blind, double-dummy, randomized, parallel group, placebo-controlled superiority study to evaluate the efficacy and safety of tafenoquine (SB-252263, WR238605) co-administered with dihydroartemisinin-piperaquine (DHA-PQP) for the radical cure of Plasmodium vivax malaria  Clinical trial  Indonesia  18/8/16 
5105-16  Motiur Rahman  Study on the incidence of Hepatitis B (HBV) and Hepatitis C (HCV) and the prevalence of progression from acute to chronic HBV and HCV infection in rural northern Vietnam  Minimal risk  Vietnam  18/8/16 
5107-16   Behzad Nadjm  Short PeRiod IncideNce sTudy of Severe Acute Respiratory Infection (SPRINT-SARI)  Minimal risk  Vietnam, Nepal  18/8/16 
33-16  Ghulam Rahim Awab  G6PD Assessment before Primaquine for radical treatment of vivax malaria (GAP study) (R46214)  Clinical trial  Afghanistan  31/8/16 
5113-16  Verena Carrara  Neonatal, clinical and neurodevelopmental outcome of neonates hospitalized for neonatal hyperbilirubinemia reaching exchange transfusion threshold in a remote setting along the Thai-Myanmar border  Minimal risk  Thailand  31/8/16 
5110-16  Stephen Baker  A descriptive study on the management of diarrhoeal disease in the community in Ho Chi Minh City, Vietnam  Minimal risk  Vietnam  1/9/16 
24-16  Abhilasha Karkey  The epidemiology of multidrug resistant hospital acquired bloodstream infections: the risks for infection and mortality in a tertiary hospital  Clinical research  Nepal, Vietnam  7/9/16 
28-16  Jane Hirst  Validation of a Proteomic Biomarker signature for the prediction of preterm birth in Vietnam  Clinical research  Vietnam  7/9/16 
5108-16  Mehul Dhorda  Prevalence survey of plasmodium falciparum antimalarial drug resistance markers in Komé, Doba, Republic of Chad  Minimal risk  Chad  7/9/16 
42-16 Jennifer Hirst  South Africa Point-of-care HbA1c study Minimal risk  South Africa  15/9/16 
5115-16  Laurence Thielemans  Field evaluation of a Point-Of-Care test for serum bilirubin levels in infants born in a tropical limited-resource setting  Minimal risk  Thailand  15/9/16 
5114-16  Anna C. Nobre  An Innovative Language Controlled Tablet-Based Cognitive Test: Harmonizing Dementia Screening  Minimal risk  South Africa  21/9/16 
38-16  Richard James Maude  Epidemiology of malaria in northeast Thailand: a case-control study  Clinical research  Thailand  28/9/16 
37-16  Bridget Wills  A matched cohort study to characterise the clinical manifestations of dengue in pregnancy and investigate the spectrum of adverse maternal and foetal outcomes  Clinical research  Vietnam  28/9/16 
5112-16  Faith Osier  Defining the merozoite targets of protective immunity against Plasmodium falciparum malaria through multi-centre cohort studies  Minimal risk  Kenya, Tanzania, Mali, Senegal, Ghana, Burkina Faso, Uganda  6/10/16 
5119-16  Phaik Yeong Cheah  Ethical challenges related to consent following implementation of a new data sharing policy  Minimal risk  Thailand  12/10/16 
43-16  Stephen Baker  Effects of albendazole treatment on gut mucosal responses and carriage of diarrheal pathogens in school children in Cu Chi, Vietnam  Clinical research  Vietnam  18/10/16 
5116-16  Niall Winters  An evaluation of a serious mobile game to improve trainee nurses knowledge and skills in emergency neonatal care in Kenyan teaching hospitals  Minimal risk  Kenya  18/10/16 
32-16  Sabina Dongol  Impact of antimicrobial resistance on outcome to ventilator associated pneumonia in a hospital setting in Kathmandu, Nepal  Clinical research  Nepal  19/10/16 
26-16  Behzad Nadjm A randomized controlled trial of continuous endotracheal cuff pressure control for the prevention of ventilator associated respiratory infections  Clinical trial  Vietnam  19/10/16 
5120-16  Amélie Julé  Data Management Practices across Malaria Clinical Research: exploring variability to understand the needs  Minimal risk Senegal, Congo  19/10/16 
45-16  Lauren Carrington  A research study of methods to prevent mosquitoes from becoming infected with, and transmitting dengue viruses  Clinical research  Vietnam  26/10/16 
5121-16 Juan Carrique-Mas  ViParc: Vietnamese Platform for Antimicrobial Reduction in Chicken Production  Minimal risk  Vietnam  3/11/16 
44-16 Guy Thwaites Detection of rat-borne pathogens in Rodent Traders in the Mekong River Delta using next-generation sequencing techniques Other research Vietnam  15/11/16 
41-16 Peter Horby Host genetic susceptibility to avian influenza A (H5N1) Clinical research Indonesia  15/11/16
5125-16 Phaik Yeong Cheah Evaluation of health-themed science theatre in Thailand Minimal risk Thailand   23/11/16
5126-16 Olga Tosas Auguet Metrics for Public Health-Perspective Surveillance of Bacterial Antibiotic Resistance (BAR) Minimal risk Kenya, Cambodia, UK   30/11/16
5122-16 Arjen Dondorp Community engagement and the acceptability of Targeted Malaria Elimination (TME) in the Greater Mekong Region: a multisite mixed methods study Minimal risk Cambodia, Myanmar, Laos, Vietnam   13/12/16
5127-16 Mark McCarthy Analysis of whole sequence data from the TOPMED study (an NHLBI funded whole genome sequencing study) Minimal risk US, UK  15/12/16 
50-16 Le Nguyen Thanh Nhan Heart Rate Variability in Children with Hand, Foot and Mouth Disease in Vietnam Clinical research Vietnam 21/12/16 
58-16 Maarten De Vos Automating the diagnosis of childhood pneumonia Other research India  21/12/16 
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